The Presence in Penicillium Funiculosum of an Inhibitor to the Antiviral Agent Helenine
نویسندگان
چکیده
The present findings indicate that the wide fluctuation observed in the antiviral activity of various crude helenine preparations may be attributable to the presence of varying amounts of inhibitor. Antiviral activity could be enhanced by removal of the inhibitor. A meaningful value for helenine titer in a preparation clearly should be determined in the inhibitor-free zone.
منابع مشابه
An Antiviral Substance from Penicillium Funiculosum
1. Helenine prevents the establishment in mice of passive viral immunity by anti-Semliki serum of swine, rabbit, or guinea pig origin. 2. A period of 12 days must elapse, between the antiviral serum administration and challenge with virus, for prevention of the establishment of passive immunity to become apparent. This period is believed to correspond to that in which injected antibody persists...
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 123 شماره
صفحات -
تاریخ انتشار 1966